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Melatonin inhibits aromatase promoter expression by regulating cyclooxygenases expression and activity in breast cancer cells

BACKGROUND: Melatonin reduces the development of breast cancer interfering with oestrogen-signalling pathways, and also inhibits aromatase activity and expression. Our objective was to study the promoters through which melatonin modifies aromatase expression, evaluate the ability of melatonin to reg...

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Detalles Bibliográficos
Autores principales: Martínez-Campa, C, González, A, Mediavilla, M D, Alonso-González, C, Alvarez-García, V, Sánchez-Barceló, E J, Cos, S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778514/
https://www.ncbi.nlm.nih.gov/pubmed/19773750
http://dx.doi.org/10.1038/sj.bjc.6605336