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Impaired TNFα-induced A20 expression in E1A/Ras-transformed cells

BACKGROUND: Tumour necrosis factor (TNF) is capable of activating the cell death pathway, and has been implicated in killing transformed cells. However, TNF also activates survival signals, including NF-κB activation and the subsequent expression of anti-apoptotic genes, leading to protection agains...

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Detalles Bibliográficos
Autores principales: Huang, H-L, Yeh, W-C, Lai, M-Z, Mirtsos, C, Chau, H, Chou, C-H, Benchimol, S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778522/
https://www.ncbi.nlm.nih.gov/pubmed/19826422
http://dx.doi.org/10.1038/sj.bjc.6605352