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Mutant p53 mediates survival of breast cancer cells

BACKGROUND: p53 is the most commonly mutated tumour-suppressor gene in human cancers. Unlike other tumour-suppressor genes, most p53 cancer mutations are missense mutations within the core domain, leading to the expression of a full-length mutant p53 protein. Accumulating evidence has indicated that...

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Detalles Bibliográficos
Autores principales: Lim, L Y, Vidnovic, N, Ellisen, L W, Leong, C-O
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778523/
https://www.ncbi.nlm.nih.gov/pubmed/19773755
http://dx.doi.org/10.1038/sj.bjc.6605335