Activity of the multikinase inhibitor dasatinib against ovarian cancer cells

BACKGROUND: Here, we explore the therapeutic potential of dasatinib, a small-molecule inhibitor that targets multiple cytosolic and membrane-bound tyrosine kinases, including members of the Src kinase family, EphA2, and focal adhesion kinase for the treatment of ovarian cancer. METHODS: We examined...

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Detalles Bibliográficos
Autores principales: Konecny, G E, Glas, R, Dering, J, Manivong, K, Qi, J, Finn, R S, Yang, G R, Hong, K-L, Ginther, C, Winterhoff, B, Gao, G, Brugge, J, Slamon, D J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778533/
https://www.ncbi.nlm.nih.gov/pubmed/19861960
http://dx.doi.org/10.1038/sj.bjc.6605381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778533/
https://www.ncbi.nlm.nih.gov/pubmed/19861960
http://dx.doi.org/10.1038/sj.bjc.6605381

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