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Gene silencing of HPV16 E6/E7 induced by promoter-targeting siRNA in SiHa cells

BACKGROUND: Recently, transcriptional gene silencing induced by small interfering RNA (siRNA) was found in mammalian and human cells. However, previous studies focused on endogenous genes. METHODS: In this study, we designed siRNA targeting the promoter of human papillomavirus 16 E6/E7 and transfect...

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Detalles Bibliográficos
Autores principales: Hong, D, Lu, W, Ye, F, Hu, Y, Xie, X
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778536/
https://www.ncbi.nlm.nih.gov/pubmed/19826423
http://dx.doi.org/10.1038/sj.bjc.6605344