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Enhanced sensitivity to androgen withdrawal due to overexpression of interleukin-6 in androgen-dependent human prostate cancer LNCaP cells

BACKGROUND: The objective of this study was to investigate the effects of interleukin-6 (IL-6) overexpression in androgen-dependent prostate cancer LNCaP cells on their phenotype under an androgen-deprived condition. METHODS: We established IL-6-overexpressing LNCaP (LNCaP/IL-6) by introducing the e...

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Detalles Bibliográficos
Autores principales: Terakawa, T, Miyake, H, Furukawa, J, Ettinger, S L, Gleave, M E, Fujisawa, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778549/
https://www.ncbi.nlm.nih.gov/pubmed/19844233
http://dx.doi.org/10.1038/sj.bjc.6605358