Pluripotent Transcription Factors Possess Distinct Roles in Normal versus Transformed Human Stem Cells

BACKGROUND: Cancer and normal stem cells (SCs) share proliferative properties of self-renewal and expression of key transcription factors (TFs). Despite similar TF identities, the functional role of specific TFs responsible for retaining SC state has yet to be examined in cancer. METHODOLOGY/PRINCIP...

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Detalles Bibliográficos
Autores principales: Ji, Junfeng, Werbowetski-Ogilvie, Tamra E., Zhong, Bonan, Hong, Seok-Ho, Bhatia, Mickie
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778551/
https://www.ncbi.nlm.nih.gov/pubmed/19956629
http://dx.doi.org/10.1371/journal.pone.0008065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778551/
https://www.ncbi.nlm.nih.gov/pubmed/19956629
http://dx.doi.org/10.1371/journal.pone.0008065

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