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Thrombospondin-2 and SPARC/osteonectin are critical regulators of bone remodeling
Thrombospondin-2 (TSP2) and osteonectin/BM-40/SPARC are matricellular proteins that are highly expressed by bone cells. Mice deficient in either of these proteins show phenotypic alterations in the skeleton, and these phenotypes are most pronounced under conditions of altered bone remodeling. For ex...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Springer Netherlands
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778593/ https://www.ncbi.nlm.nih.gov/pubmed/19862642 http://dx.doi.org/10.1007/s12079-009-0076-0 |