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Thrombospondin-2 and SPARC/osteonectin are critical regulators of bone remodeling

Thrombospondin-2 (TSP2) and osteonectin/BM-40/SPARC are matricellular proteins that are highly expressed by bone cells. Mice deficient in either of these proteins show phenotypic alterations in the skeleton, and these phenotypes are most pronounced under conditions of altered bone remodeling. For ex...

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Detalles Bibliográficos
Autores principales: Delany, Anne M., Hankenson, Kurt David
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778593/
https://www.ncbi.nlm.nih.gov/pubmed/19862642
http://dx.doi.org/10.1007/s12079-009-0076-0