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Conformational changes and protein stability of the pro-apoptotic protein Bax
Pro-apoptotic Bax is a soluble and monomeric protein under normal physiological conditions. Upon its activation substantial structural rearrangements occur: The protein inserts into the mitochondrial outer membrane and forms higher molecular weight oligomers. Subsequently, the cells can undergo apop...
| Autores principales: | , |
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| Format: | Texto |
| Sprog: | English |
| Udgivet: |
Springer US
2009
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| Fag: | |
| Online adgang: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778690/ https://www.ncbi.nlm.nih.gov/pubmed/19255832 http://dx.doi.org/10.1007/s10863-009-9202-1 |