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Accelerating regional atrophy rates in the progression from normal aging to Alzheimer’s disease

We investigated progression of atrophy in vivo, in Alzheimer’s disease (AD), and mild cognitive impairment (MCI). We included 64 patients with AD, 44 with MCI and 34 controls with serial MRI examinations (interval 1.8 ± 0.7 years). A nonlinear registration algorithm (fluid) was used to calculate atr...

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Detalles Bibliográficos
Autores principales: Sluimer, Jasper D., van der Flier, Wiesje M., Karas, Giorgos B., van Schijndel, Ronald, Barnes, Josephine, Boyes, Richard G., Cover, Keith S., Olabarriaga, Sílvia D., Fox, Nick C., Scheltens, Philip, Vrenken, Hugo, Barkhof, Frederik
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778773/
https://www.ncbi.nlm.nih.gov/pubmed/19618189
http://dx.doi.org/10.1007/s00330-009-1512-5