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The Origin Recognition Complex Interacts with a Subset of Metabolic Genes Tightly Linked to Origins of Replication

The origin recognition complex (ORC) marks chromosomal sites as replication origins and is essential for replication initiation. In yeast, ORC also binds to DNA elements called silencers, where its primary function is to recruit silent information regulator (SIR) proteins to establish transcriptiona...

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Detalles Bibliográficos
Autores principales: Shor, Erika, Warren, Christopher L., Tietjen, Joshua, Hou, Zhonggang, Müller, Ulrika, Alborelli, Ilaria, Gohard, Florence H., Yemm, Adrian I., Borisov, Lev, Broach, James R., Weinreich, Michael, Nieduszynski, Conrad A., Ansari, Aseem Z., Fox, Catherine A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778871/
https://www.ncbi.nlm.nih.gov/pubmed/19997491
http://dx.doi.org/10.1371/journal.pgen.1000755