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The Origin Recognition Complex Interacts with a Subset of Metabolic Genes Tightly Linked to Origins of Replication
The origin recognition complex (ORC) marks chromosomal sites as replication origins and is essential for replication initiation. In yeast, ORC also binds to DNA elements called silencers, where its primary function is to recruit silent information regulator (SIR) proteins to establish transcriptiona...
Autores principales: | Shor, Erika, Warren, Christopher L., Tietjen, Joshua, Hou, Zhonggang, Müller, Ulrika, Alborelli, Ilaria, Gohard, Florence H., Yemm, Adrian I., Borisov, Lev, Broach, James R., Weinreich, Michael, Nieduszynski, Conrad A., Ansari, Aseem Z., Fox, Catherine A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778871/ https://www.ncbi.nlm.nih.gov/pubmed/19997491 http://dx.doi.org/10.1371/journal.pgen.1000755 |
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