Expression of an IKKγ Splice Variant Determines IRF3 and Canonical NF-κB Pathway Utilization in ssRNA Virus Infection

Single stranded RNA (ssRNA) virus infection activates the retinoic acid inducible gene I (RIG-I)- mitochondrial antiviral signaling (MAVS) complex, a complex that coordinates the host innate immune response via the NF-κB and IRF3 pathways. Recent work has shown that the IκB kinase (IKK)γ scaffolding...

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Detalles Bibliográficos
Autores principales: Liu, Ping, Lu, Muping, Tian, Bing, Li, Kui, Garofalo, Roberto P., Prusak, Deborah, Wood, Thomas G., Brasier, Allan R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778955/
https://www.ncbi.nlm.nih.gov/pubmed/19956647
http://dx.doi.org/10.1371/journal.pone.0008079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778955/
https://www.ncbi.nlm.nih.gov/pubmed/19956647
http://dx.doi.org/10.1371/journal.pone.0008079

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