Mechanism for CCC DNA Synthesis in Hepadnaviruses

Hepadnavirus replication requires the synthesis of a covalently closed circular (CCC) DNA from the relaxed circular (RC) viral genome by an unknown mechanism. CCC DNA formation could require enzymatic activities of the viral reverse transcriptase (RT), or cellular DNA repair enzymes, or both. Physic...

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Detalles Bibliográficos
Autores principales: Sohn, Ji A., Litwin, Samuel, Seeger, Christoph
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778999/
https://www.ncbi.nlm.nih.gov/pubmed/19956651
http://dx.doi.org/10.1371/journal.pone.0008093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778999/
https://www.ncbi.nlm.nih.gov/pubmed/19956651
http://dx.doi.org/10.1371/journal.pone.0008093

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