Application of an integrated physical and functional screening approach to identify inhibitors of the Wnt pathway

Large-scale proteomic approaches have been used to study signaling pathways. However, identification of biologically relevant hits from a single screen remains challenging due to limitations inherent in each individual approach. To overcome these limitations, we implemented an integrated, multi-dime...

Descripción completa

Detalles Bibliográficos
Autores principales: Miller, Bryan W, Lau, Garnet, Grouios, Chris, Mollica, Emanuela, Barrios-Rodiles, Miriam, Liu, Yongmei, Datti, Alessandro, Morris, Quaid, Wrana, Jeffrey L, Attisano, Liliana
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779086/
https://www.ncbi.nlm.nih.gov/pubmed/19888210
http://dx.doi.org/10.1038/msb.2009.72

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779086/
https://www.ncbi.nlm.nih.gov/pubmed/19888210
http://dx.doi.org/10.1038/msb.2009.72

Ejemplares similares