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Application of an integrated physical and functional screening approach to identify inhibitors of the Wnt pathway
Large-scale proteomic approaches have been used to study signaling pathways. However, identification of biologically relevant hits from a single screen remains challenging due to limitations inherent in each individual approach. To overcome these limitations, we implemented an integrated, multi-dime...
Autores principales: | Miller, Bryan W, Lau, Garnet, Grouios, Chris, Mollica, Emanuela, Barrios-Rodiles, Miriam, Liu, Yongmei, Datti, Alessandro, Morris, Quaid, Wrana, Jeffrey L, Attisano, Liliana |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779086/ https://www.ncbi.nlm.nih.gov/pubmed/19888210 http://dx.doi.org/10.1038/msb.2009.72 |
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