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Cross-Talk between Oxysterols and Glucocorticoids: Differential Regulation of Secreted Phopholipase A2 and Impact on Oligodendrocyte Death

BACKGROUND: Oxysterols are oxidized forms of cholesterol. They have been shown to be implicated in cholesterol turnover, inflammation and in neurodegenerative diseases such as Alzheimer's disease and multiple sclerosis. Glial cells are targets of oxysterols: they inhibit astrocyte proliferation...

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Detalles Bibliográficos
Autores principales: Trousson, Amalia, Makoukji, Joelle, Petit, Patrice X., Bernard, Sophie, Slomianny, Christian, Schumacher, Michael, Massaad, Charbel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779104/
https://www.ncbi.nlm.nih.gov/pubmed/19956653
http://dx.doi.org/10.1371/journal.pone.0008080