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Drevogenin D prevents selenite-induced oxidative stress and calpain activation in cultured rat lens

PURPOSE: Selenite-induced cataractogenesis is mediated by oxidative stress, accumulation of calcium and activation of lenticular calpains. Calpains are a super family of Ca(2+) dependent proteases, which are involved in lens protein proteolysis and insolubilization. Many inhibitors could prevent cal...

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Detalles Bibliográficos
Autores principales: Biju, P.G., Rooban, B. N., Lija, Y., Devi, V. Gayathri, Sahasranamam, V., Abraham, Annie
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779145/
https://www.ncbi.nlm.nih.gov/pubmed/17653057