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Drevogenin D prevents selenite-induced oxidative stress and calpain activation in cultured rat lens
PURPOSE: Selenite-induced cataractogenesis is mediated by oxidative stress, accumulation of calcium and activation of lenticular calpains. Calpains are a super family of Ca(2+) dependent proteases, which are involved in lens protein proteolysis and insolubilization. Many inhibitors could prevent cal...
Autores principales: | Biju, P.G., Rooban, B. N., Lija, Y., Devi, V. Gayathri, Sahasranamam, V., Abraham, Annie |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Molecular Vision
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779145/ https://www.ncbi.nlm.nih.gov/pubmed/17653057 |
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