Analysis of six candidate genes as potential modifiers of disease expression in canine XLPRA1, a model for human X-linked retinitis pigmentosa 3

PURPOSE: Canine X-linked progressive retinal atrophy (XLPRA) is caused by mutations in RPGR exon ORF15, which is also a mutation hotspot in human X-linked retinitis pigmentosa 3 (RP3). The XLPRA1 form of disease has shown extensive phenotypic variability in a colony of dogs that all inherited the sa...

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Detalles Bibliográficos
Autores principales: Guyon, Richard, Pearce-Kelling, Susan E., Zeiss, Caroline J., Acland, Gregory M., Aguirre, Gustavo D.
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779147/
https://www.ncbi.nlm.nih.gov/pubmed/17653054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779147/
https://www.ncbi.nlm.nih.gov/pubmed/17653054

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