Capacity for stochastic self-renewal and differentiation in mammalian spermatogonial stem cells

Mammalian spermatogenesis is initiated and sustained by spermatogonial stem cells (SSCs) through self-renewal and differentiation. The basic question of whether SSCs have the potential to specify self-renewal and differentiation in a cell-autonomous manner has yet to be addressed. Here, we show that...

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Detalles Bibliográficos
Autores principales: Wu, Zhuoru, Luby-Phelps, Katherine, Bugde, Abhijit, Molyneux, Laura A., Denard, Bray, Li, Wen-Hong, Süel, Gürol M., Garbers, David L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779229/
https://www.ncbi.nlm.nih.gov/pubmed/19948499
http://dx.doi.org/10.1083/jcb.200907047