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Capacity for stochastic self-renewal and differentiation in mammalian spermatogonial stem cells
Mammalian spermatogenesis is initiated and sustained by spermatogonial stem cells (SSCs) through self-renewal and differentiation. The basic question of whether SSCs have the potential to specify self-renewal and differentiation in a cell-autonomous manner has yet to be addressed. Here, we show that...
Autores principales: | Wu, Zhuoru, Luby-Phelps, Katherine, Bugde, Abhijit, Molyneux, Laura A., Denard, Bray, Li, Wen-Hong, Süel, Gürol M., Garbers, David L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779229/ https://www.ncbi.nlm.nih.gov/pubmed/19948499 http://dx.doi.org/10.1083/jcb.200907047 |
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