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Lte1 contributes to Bfa1 localization rather than stimulating nucleotide exchange by Tem1

Lte1 is a mitotic regulator long envisaged as a guanosine nucleotide exchange factor (GEF) for Tem1, the small guanosine triphosphatase governing activity of the Saccharomyces cerevisiae mitotic exit network. We demonstrate that this model requires reevaluation. No GEF activity was detectable in vit...

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Detalles Bibliográficos
Autores principales: Geymonat, Marco, Spanos, Adonis, de Bettignies, Geoffroy, Sedgwick, Steven G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779235/
https://www.ncbi.nlm.nih.gov/pubmed/19948498
http://dx.doi.org/10.1083/jcb.200905114