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Lte1 contributes to Bfa1 localization rather than stimulating nucleotide exchange by Tem1
Lte1 is a mitotic regulator long envisaged as a guanosine nucleotide exchange factor (GEF) for Tem1, the small guanosine triphosphatase governing activity of the Saccharomyces cerevisiae mitotic exit network. We demonstrate that this model requires reevaluation. No GEF activity was detectable in vit...
Autores principales: | Geymonat, Marco, Spanos, Adonis, de Bettignies, Geoffroy, Sedgwick, Steven G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779235/ https://www.ncbi.nlm.nih.gov/pubmed/19948498 http://dx.doi.org/10.1083/jcb.200905114 |
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