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Noninvasive quantification of (18)F-FLT human brain PET for the assessment of tumour proliferation in patients with high-grade glioma

PURPOSE: Compartmental modelling of 3′-deoxy-3′-[(18)F]-fluorothymidine ((18)F-FLT) PET-derived kinetics provides a method for noninvasive assessment of the proliferation rate of gliomas. Such analyses, however, require an input function generally derived by serial blood sampling and counting. In th...

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Detalles Bibliográficos
Autores principales: Backes, Heiko, Ullrich, Roland, Neumaier, Bernd, Kracht, Lutz, Wienhard, Klaus, Jacobs, Andreas H.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779371/
https://www.ncbi.nlm.nih.gov/pubmed/19672593
http://dx.doi.org/10.1007/s00259-009-1244-4