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Lymphoma and Myeloma Cell Resistance to Cytotoxic Agents and Ionizing Radiations Is Not Affected by Exposure to Anti–IL-6 Antibody

BACKGROUND: Production of high levels of IL-6 is often correlated with resistance to cytotoxics or ionizing radiations, in cancer cell lines as in various cancer patients. We investigated whether monoclonal antibodies directed against IL-6 may enable to reverse resistance of cancer cell lines. METHO...

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Detalles Bibliográficos
Autores principales: Gougelet, Angélique, Mansuy, Adeline, Blay, Jean-Yves, Alberti, Laurent, Vermot-Desroches, Claudine
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779452/
https://www.ncbi.nlm.nih.gov/pubmed/19956602
http://dx.doi.org/10.1371/journal.pone.0008026