Human pregnancy-associated malaria-specific B cells target polymorphic, conformational epitopes in VAR2CSA

Pregnancy-associated malaria (PAM) is caused by Plasmodium falciparum-infected erythrocytes (IEs) that bind to chondroitin sulphate A (CSA) in the placenta by PAM-associated clonally variant surface antigens (VSA). Pregnancy-specific VSA (VSA(PAM)), which include the PfEMP1 variant VAR2CSA, are targ...

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Detalles Bibliográficos
Autores principales: Barfod, Lea, Bernasconi, Nadia L, Dahlbäck, Madeleine, Jarrossay, David, Andersen, Pernille Haste, Salanti, Ali, Ofori, Michael F, Turner, Louise, Resende, Mafalda, Nielsen, Morten A, Theander, Thor G, Sallusto, Federica, Lanzavecchia, Antonio, Hviid, Lars
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2007
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779471/
https://www.ncbi.nlm.nih.gov/pubmed/17176260
http://dx.doi.org/10.1111/j.1365-2958.2006.05503.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779471/
https://www.ncbi.nlm.nih.gov/pubmed/17176260
http://dx.doi.org/10.1111/j.1365-2958.2006.05503.x

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