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Cross Species Genomic Analysis Identifies a Mouse Model as Undifferentiated Pleomorphic Sarcoma/Malignant Fibrous Histiocytoma

Undifferentiated pleomorphic sarcoma/Malignant Fibrous Histiocytoma (MFH) is one of the most common subtypes of human soft tissue sarcoma. Using cross species genomic analysis, we define a geneset from the LSL-Kras(G12D); Trp53(Flox/Flox) mouse model of soft tissue sarcoma that is highly enriched in...

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Detalles Bibliográficos
Autores principales: Mito, Jeffrey K., Riedel, Richard F., Dodd, Leslie, Lahat, Guy, Lazar, Alexander J., Dodd, Rebecca D., Stangenberg, Lars, Eward, William C., Hornicek, Francis J., Yoon, Sam S., Brigman, Brian E., Jacks, Tyler, Lev, Dina, Mukherjee, Sayan, Kirsch, David G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779485/
https://www.ncbi.nlm.nih.gov/pubmed/19956606
http://dx.doi.org/10.1371/journal.pone.0008075