Integrating In Silico and In Vitro Analysis of Peptide Binding Affinity to HLA-Cw*0102: A Bioinformatic Approach to the Prediction of New Epitopes

BACKGROUND: Predictive models of peptide-Major Histocompatibility Complex (MHC) binding affinity are important components of modern computational immunovaccinology. Here, we describe the development and deployment of a reliable peptide-binding prediction method for a previously poorly-characterized...

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Detalles Bibliográficos
Autores principales: Walshe, Valerie A., Hattotuwagama, Channa K., Doytchinova, Irini A., Wong, MaiLee, Macdonald, Isabel K., Mulder, Arend, Claas, Frans H. J., Pellegrino, Pierre, Turner, Jo, Williams, Ian, Turnbull, Emma L., Borrow, Persephone, Flower, Darren R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779488/
https://www.ncbi.nlm.nih.gov/pubmed/19956609
http://dx.doi.org/10.1371/journal.pone.0008095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779488/
https://www.ncbi.nlm.nih.gov/pubmed/19956609
http://dx.doi.org/10.1371/journal.pone.0008095

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