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Quantifying the treatment efficacy of reverse transcriptase inhibitors: new analyses of clinical data based on within-host modeling

BACKGROUND: Current measures of the clinical efficacy of antiretroviral therapy (ART) in the treatment of HIV include the change in HIV RNA in the plasma and the gain in CD4 cells. METHODS: We propose new measures for evaluating the efficacy of treatment that is based upon combinations of non-nucleo...

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Detalles Bibliográficos
Autores principales: Breban, Romulus, Napravnik, Sonia, Kahn, James, Blower, Sally
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779499/
https://www.ncbi.nlm.nih.gov/pubmed/19922681
http://dx.doi.org/10.1186/1471-2458-9-S1-S11