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Quantifying the treatment efficacy of reverse transcriptase inhibitors: new analyses of clinical data based on within-host modeling
BACKGROUND: Current measures of the clinical efficacy of antiretroviral therapy (ART) in the treatment of HIV include the change in HIV RNA in the plasma and the gain in CD4 cells. METHODS: We propose new measures for evaluating the efficacy of treatment that is based upon combinations of non-nucleo...
Autores principales: | Breban, Romulus, Napravnik, Sonia, Kahn, James, Blower, Sally |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779499/ https://www.ncbi.nlm.nih.gov/pubmed/19922681 http://dx.doi.org/10.1186/1471-2458-9-S1-S11 |
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