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Humoral Immune Response to Mixed PfAMA1 Alleles; Multivalent PfAMA1 Vaccines Induce Broad Specificity

Apical Membrane Antigen 1 (AMA1), a merozoite protein essential for red cell invasion, is a candidate malaria vaccine component. Immune responses to AMA1 can protect in experimental animal models and antibodies isolated from AMA1-vaccinated or malaria-exposed humans can inhibit parasite multiplicati...

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Detalles Bibliográficos
Autores principales: Kusi, Kwadwo A., Faber, Bart W., Thomas, Alan W., Remarque, Edmond J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779588/
https://www.ncbi.nlm.nih.gov/pubmed/19956619
http://dx.doi.org/10.1371/journal.pone.0008110