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Helicobacter pylori Type IV Secretion Apparatus Exploits β1 Integrin in a Novel RGD-Independent Manner

Translocation of the Helicobacter pylori (Hp) cytotoxin-associated gene A (CagA) effector protein via the cag-Type IV Secretion System (T4SS) into host cells is a major risk factor for severe gastric diseases, including gastric cancer. However, the mechanism of translocation and the requirements fro...

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Detalles Bibliográficos
Autores principales: Jiménez-Soto, Luisa F., Kutter, Stefan, Sewald, Xaver, Ertl, Claudia, Weiss, Evelyn, Kapp, Ulrike, Rohde, Manfred, Pirch, Torsten, Jung, Kirsten, Retta, S. Francesco, Terradot, Laurent, Fischer, Wolfgang, Haas, Rainer
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779590/
https://www.ncbi.nlm.nih.gov/pubmed/19997503
http://dx.doi.org/10.1371/journal.ppat.1000684