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Sphingosine Kinase-1 Is Central to Androgen-Regulated Prostate Cancer Growth and Survival
BACKGROUND: Sphingosine kinase-1 (SphK1) is an oncogenic lipid kinase notably involved in response to anticancer therapies in prostate cancer. Androgens regulate prostate cancer cell proliferation, and androgen deprivation therapy is the standard of care in the management of patients with advanced d...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779655/ https://www.ncbi.nlm.nih.gov/pubmed/19956567 http://dx.doi.org/10.1371/journal.pone.0008048 |