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Sphingosine Kinase-1 Is Central to Androgen-Regulated Prostate Cancer Growth and Survival

BACKGROUND: Sphingosine kinase-1 (SphK1) is an oncogenic lipid kinase notably involved in response to anticancer therapies in prostate cancer. Androgens regulate prostate cancer cell proliferation, and androgen deprivation therapy is the standard of care in the management of patients with advanced d...

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Detalles Bibliográficos
Autores principales: Dayon, Audrey, Brizuela, Leyre, Martin, Claire, Mazerolles, Catherine, Pirot, Nelly, Doumerc, Nicolas, Nogueira, Leonor, Golzio, Muriel, Teissié, Justin, Serre, Guy, Rischmann, Pascal, Malavaud, Bernard, Cuvillier, Olivier
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779655/
https://www.ncbi.nlm.nih.gov/pubmed/19956567
http://dx.doi.org/10.1371/journal.pone.0008048