The molecular basis for stability of heterochromatin-mediated silencing in mammals

The archetypal epigenetic phenomenon of position effect variegation (PEV) in Drosophila occurs when a gene is brought abnormally close to heterochromatin, resulting in stochastic silencing of the affected gene in a proportion of cells that would normally express it. PEV has been instrumental in unra...

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Detalles Bibliográficos
Autores principales: Hiragami-Hamada, Kyoko, Xie, Sheila Q, Saveliev, Alexander, Uribe-Lewis, Santiago, Pombo, Ana, Festenstein, Richard
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779788/
https://www.ncbi.nlm.nih.gov/pubmed/19889207
http://dx.doi.org/10.1186/1756-8935-2-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779788/
https://www.ncbi.nlm.nih.gov/pubmed/19889207
http://dx.doi.org/10.1186/1756-8935-2-14

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