Role of the transcription factor C/EBPδ in a regulatory circuit that discriminates between transient and persistent Toll-like receptor 4-induced signals

The innate immune system is a two-edged sword; it is absolutely required for host defense against infection but, uncontrolled, can trigger a plethora of inflammatory diseases. Here we used systems biology approaches to predict and validate a gene regulatory network involving a dynamic interplay betw...

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Detalles Bibliográficos
Autores principales: Litvak, Vladimir, Ramsey, Stephen A., Rust, Alistair G., Zak, Daniel E., Kennedy, Kathleen A., Lampano, Aaron E., Nykter, Matti, Shmulevich, Ilya, Aderem, Alan
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780024/
https://www.ncbi.nlm.nih.gov/pubmed/19270711
http://dx.doi.org/10.1038/ni.1721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780024/
https://www.ncbi.nlm.nih.gov/pubmed/19270711
http://dx.doi.org/10.1038/ni.1721

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