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Central Role of the Holliday Junction Helicase RuvAB in vlsE Recombination and Infectivity of Borrelia burgdorferi

Antigenic variation plays a vital role in the pathogenesis of many infectious bacteria and protozoa including Borrelia burgdorferi, the causative agent of Lyme disease. VlsE, a 35 kDa surface-exposed lipoprotein, undergoes antigenic variation during B. burgdorferi infection of mammalian hosts, and i...

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Detalles Bibliográficos
Autores principales: Lin, Tao, Gao, Lihui, Edmondson, Diane G., Jacobs, Mary B., Philipp, Mario T., Norris, Steven J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780311/
https://www.ncbi.nlm.nih.gov/pubmed/19997622
http://dx.doi.org/10.1371/journal.ppat.1000679