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The C-Terminal Sequence of RhoB Directs Protein Degradation through an Endo-Lysosomal Pathway

BACKGROUND: Protein degradation is essential for cell homeostasis. Targeting of proteins for degradation is often achieved by specific protein sequences or posttranslational modifications such as ubiquitination. METHODOLOGY/PRINCIPAL FINDINGS: By using biochemical and genetic tools we have monitored...

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Detalles Bibliográficos
Autores principales: Pérez-Sala, Dolores, Boya, Patricia, Ramos, Irene, Herrera, Mónica, Stamatakis, Konstantinos
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780327/
https://www.ncbi.nlm.nih.gov/pubmed/19956591
http://dx.doi.org/10.1371/journal.pone.0008117