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The C-Terminal Sequence of RhoB Directs Protein Degradation through an Endo-Lysosomal Pathway
BACKGROUND: Protein degradation is essential for cell homeostasis. Targeting of proteins for degradation is often achieved by specific protein sequences or posttranslational modifications such as ubiquitination. METHODOLOGY/PRINCIPAL FINDINGS: By using biochemical and genetic tools we have monitored...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780327/ https://www.ncbi.nlm.nih.gov/pubmed/19956591 http://dx.doi.org/10.1371/journal.pone.0008117 |