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NOTCH3 SIGNALING IS REQUIRED FOR THE DEVELOPMENT OF PULMONARY ARTERIAL HYPERTENSION

Notch receptor signaling is implicated in controlling smooth muscle cell proliferation and maintaining smooth muscle cells in an undifferentiated state. Pulmonary arterial hypertension is a disease characterized by excessive vascular smooth muscle cell proliferation in small pulmonary arteries, lead...

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Detalles Bibliográficos
Autores principales: Li, Xiaodong, Zhang, Xiaoxue, Leathers, Robin, Makino, Ayako, Huang, Chengqun, Parsa, Pouria, Macias, Jesus, Yuan, Jason X.-J., Jamieson, Stuart W., Thistlethwaite, Patricia A.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780347/
https://www.ncbi.nlm.nih.gov/pubmed/19855400
http://dx.doi.org/10.1038/nm.2021