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NOTCH3 SIGNALING IS REQUIRED FOR THE DEVELOPMENT OF PULMONARY ARTERIAL HYPERTENSION
Notch receptor signaling is implicated in controlling smooth muscle cell proliferation and maintaining smooth muscle cells in an undifferentiated state. Pulmonary arterial hypertension is a disease characterized by excessive vascular smooth muscle cell proliferation in small pulmonary arteries, lead...
Autores principales: | Li, Xiaodong, Zhang, Xiaoxue, Leathers, Robin, Makino, Ayako, Huang, Chengqun, Parsa, Pouria, Macias, Jesus, Yuan, Jason X.-J., Jamieson, Stuart W., Thistlethwaite, Patricia A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780347/ https://www.ncbi.nlm.nih.gov/pubmed/19855400 http://dx.doi.org/10.1038/nm.2021 |
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