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Characterization of two classes of small molecule inhibitors of Arp2/3 complex

Polymerization of actin filaments directed by the Arp2/3 complex supports many types of cellular movements1. However, questions remain regarding the relative contributions of Arp2/3 complex versus other mechanisms of actin filament nucleation to processes such as path finding by neuronal growth cone...

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Detalles Bibliográficos
Autores principales: Nolen, B.J., Tomasevic, N., Russell, A., Pierce, D.W., Jia, Z., McCormick, C.D., Hartman, J., Sakowicz, R., Pollard, T.D.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780427/
https://www.ncbi.nlm.nih.gov/pubmed/19648907
http://dx.doi.org/10.1038/nature08231