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Liver fibrosis secondary to bile duct injury: correlation of Smad7 with TGF-β and extracellular matrix proteins

BACKGROUND: Liver fibrosis is the result of continuous liver injury stemming from different etiological factors. Bile duct injury induces an altered expression of TGF-β, which has an important role in liver fibrosis because this cytokine induces the expression of target genes such as collagens, PAI-...

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Detalles Bibliográficos
Autores principales: del Pilar Alatorre-Carranza, María, Miranda-Díaz, Alejandra, Yañez-Sánchez, Irinea, Pizano-Martínez, Oscar, Hermosillo-Sandoval, José M, Vázquez-Del Mercado, Mónica, Hernández-Hoyos, Sebastián, Martínez-Abundis, Ricardo, Fafutis-Morris, Mary, Segura-Ortega, Jorge, Delgado-Rizo, Vidal
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780448/
https://www.ncbi.nlm.nih.gov/pubmed/19878580
http://dx.doi.org/10.1186/1471-230X-9-81