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RT-SHIV, an infectious CCR5-tropic chimeric virus suitable for evaluating HIV reverse transcriptase inhibitors in macaque models

BACKGROUND: Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are an important category of drugs for both chemotherapy and prevention of human immunodeficiency virus type 1 (HIV-1) infection. However, current non-human primate (NHP) models utilizing simian immunodeficiency virus (SIV) or comm...

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Detalles Bibliográficos
Autores principales: Jiang, Yonghou, Tian, Baoping, Saifuddin, Mohammed, Agy, Michael B, Emau, Peter, Cairns, J Scott, Tsai, Che-Chung
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780452/
https://www.ncbi.nlm.nih.gov/pubmed/19891783
http://dx.doi.org/10.1186/1742-6405-6-23