Cargando…
RT-SHIV, an infectious CCR5-tropic chimeric virus suitable for evaluating HIV reverse transcriptase inhibitors in macaque models
BACKGROUND: Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are an important category of drugs for both chemotherapy and prevention of human immunodeficiency virus type 1 (HIV-1) infection. However, current non-human primate (NHP) models utilizing simian immunodeficiency virus (SIV) or comm...
Autores principales: | Jiang, Yonghou, Tian, Baoping, Saifuddin, Mohammed, Agy, Michael B, Emau, Peter, Cairns, J Scott, Tsai, Che-Chung |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780452/ https://www.ncbi.nlm.nih.gov/pubmed/19891783 http://dx.doi.org/10.1186/1742-6405-6-23 |
Ejemplares similares
-
Post-exposure prophylaxis for SIV revisited: Animal model for HIV prevention
por: Emau, Peter, et al.
Publicado: (2006) -
Antibody-based CCR5 blockade protects Macaques from mucosal SHIV transmission
por: Chang, Xiao L., et al.
Publicado: (2021) -
RT-SHIV subpopulation dynamics in infected macaques during anti-HIV therapy
por: Shao, Wei, et al.
Publicado: (2009) -
Variation of Human Immunodeficiency Virus Type-1 Reverse Transcriptase within the Simian Immunodeficiency Virus Genome of RT-SHIV
por: Wadford, Debra A., et al.
Publicado: (2014) -
A MIV-150/Zinc Acetate Gel Inhibits SHIV-RT Infection in Macaque Vaginal Explants
por: Barnable, Patrick, et al.
Publicado: (2014)