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STAT1-dependent expression of energy metabolic pathways links tumour growth and radioresistance to the Warburg effect

BACKGROUND: The Signal Transducer and Activator of Transcription 1 (STAT1) has traditionally been regarded as a transmitter of interferon signaling and a pro-apoptotic tumour suppressor. Recent data have identified new functions of STAT1 associated with tumourigenesis and resistance to genotoxic str...

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Detalles Bibliográficos
Autores principales: Pitroda, Sean P, Wakim, Bassam T, Sood, Ravi F, Beveridge, Mara G, Beckett, Michael A, MacDermed, Dhara M, Weichselbaum, Ralph R, Khodarev, Nikolai N
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780454/
https://www.ncbi.nlm.nih.gov/pubmed/19891767
http://dx.doi.org/10.1186/1741-7015-7-68