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STAT1-dependent expression of energy metabolic pathways links tumour growth and radioresistance to the Warburg effect
BACKGROUND: The Signal Transducer and Activator of Transcription 1 (STAT1) has traditionally been regarded as a transmitter of interferon signaling and a pro-apoptotic tumour suppressor. Recent data have identified new functions of STAT1 associated with tumourigenesis and resistance to genotoxic str...
Autores principales: | Pitroda, Sean P, Wakim, Bassam T, Sood, Ravi F, Beveridge, Mara G, Beckett, Michael A, MacDermed, Dhara M, Weichselbaum, Ralph R, Khodarev, Nikolai N |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780454/ https://www.ncbi.nlm.nih.gov/pubmed/19891767 http://dx.doi.org/10.1186/1741-7015-7-68 |
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