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How Many Genetic Variants Remain to Be Discovered?
A great majority of genetic markers discovered in recent genome-wide association studies have small effect sizes, and they explain only a small fraction of the genetic contribution to the diseases. How many more variants can we expect to discover and what study sizes are needed? We derive the connec...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780697/ https://www.ncbi.nlm.nih.gov/pubmed/19956539 http://dx.doi.org/10.1371/journal.pone.0007969 |