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Down Regulation of Genes Involved in T Cell Polarity and Motility during the Induction of Heart Allograft Tolerance by Allochimeric MHC I

BACKGROUND: The allochimeric MHC class I molecule [α1h1/u]-RT1.Aa that contains donor-type (Wistar Furth, WF; RT1u) epitopes displayed on recipient-type (ACI, RT1a) administered in conjunction with sub-therapeutic dose of cyclosporine (CsA) induces indefinite survival of heterotopic cardiac allograf...

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Detalles Bibliográficos
Autores principales: Lisik, Wojciech, Tejpal, Neelam, Gong, Yongquan, Skelton, T. Spencer, Ganachari, Malathesh, Bremer, Eric G., Kloc, Malgorzata, Ghobrial, Rafik M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780702/
https://www.ncbi.nlm.nih.gov/pubmed/19956540
http://dx.doi.org/10.1371/journal.pone.0008020