Carbon Monoxide Blocks Lipopolysaccharide-Induced Gene Expression by Interfering with Proximal TLR4 to NF-κB Signal Transduction in Human Monocytes

Carbon monoxide (CO) is an endogenous messenger that suppresses inflammation, modulates apoptosis and promotes vascular remodeling. Here, microarrays were employed to globally characterize the CO (250 ppm) suppression of early (1 h) LPS-induced inflammation in human monocytic THP-1 cells. CO suppres...

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Detalles Bibliográficos
Autores principales: Chhikara, Maneesha, Wang, Shuibang, Kern, Steven J., Ferreyra, Gabriela A., Barb, Jennifer J., Munson, Peter J., Danner, Robert L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780718/
https://www.ncbi.nlm.nih.gov/pubmed/19956541
http://dx.doi.org/10.1371/journal.pone.0008139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780718/
https://www.ncbi.nlm.nih.gov/pubmed/19956541
http://dx.doi.org/10.1371/journal.pone.0008139

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